Buy Nembutal Sodium Oral Solution

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Description

Nembutal Sodium 50ml

Nembutal Sodium 50ml a short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. Also, prescribed more frequently for sleep induction than for sedation. Therefore, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)

Pharmacodynamics of Nembutal Sodium 50ml

Pentobarbital, a barbiturate, is for the treatment of short term insomnia. Also, It belongs to a group of medicines called central nervous system (CNS) depressants. That induces drowsiness and relieve tension or nervousness. Also, Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation.

Molar mass226.27 g/mol
Formula: C11H18N2O3
Metabolism: Liver
Elimination half-life: 15–48 hours
License data: US FDA: Pentobarbital
ATC code: N05CA01 (WHO) QN51AA01 (WHO)

How to buy Nembutal Sodium 50ml ?

Nembutal Sodium Solution CII

(Pentobarbital Sodium Injection, USP)

novaplusTM+

Vials

How to supplied

NEMBUTAL Sodium Solution (Pentobarbital Sodium Injection, USP) is available in the following sizes: 20-mL multiple-dose vial, 1 g per vial (NDC 17478-181-20); and 50-mL multiple-dose vial, 2.5 g per vial (NDC 17478-181-50).
Each mL contains:
Pentobarbital Sodium, derivative of barbituric acid………………… 50 mg
Propylene glycol……………………………………………………………………40% v/v
Alcohol………………………………………………………………………………… 10%
Water for Injection………………………………………………………………… qs
(pH adjusted to approximately 9.5 with hydrochloric acid and/or sodium hydroxide.)
Vial stoppers are latex free.
Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at 20° to 25°C (68° to 77°F), however, brief excursions are permitted between 15° to 30°C (59° to 86°F). See USP controlled room temperature.

CLINICAL PHARMACOLOGY OF Nembutal Sodium 50ml

Barbiturates are capable of producing all levels of CNS mood alteration from excitation to mild sedation, to hypnosis, and deep coma. Also, Overdosage can produce death. Therefore, In high enough therapeutic doses, barbiturates induce anesthesia.

Barbiturates depress the sensory cortex. Decrease motor activity, alter cerebellar function, and produce drowsiness, sedation, and hypnosis.

How If Functions :

Barbiturate-induced sleep differs from physiological sleep. Also, Sleep laboratory demonstrate that barbiturates reduce the amount of time spent in the rapid eye movement (REM). The phase of sleep or dreaming stage. Also, Stages III and IV sleep decrease. Therefore, Following abrupt cessation of barbiturates used regularly. Patients experience increase dreaming, nightmares, and/or insomnia. Therefore, withdrawal of a single therapeutic dose over 5 or 6 days recommend lessening the REM rebound and disturbed sleep which contribute to drug withdrawal syndrome (for example, decrease the dose from 3 to 2 doses a day for 1 week).

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